
Spine Pain Masquerading as Knee Pain? Expert Explains!
Is your knee pain really coming from your knee, or could something deeper be going on?
In this podcast episode, learn the surprising link between knee pain and spine issues that could completely change how you understand your symptoms. If you've been chasing joint treatments with little relief, you might be missing the bigger picture.
Don’t miss this eye-opening episode that unpacks the knee pain and spine issues connection, your long-awaited relief might start here. Tune in before you spend another day treating the wrong problem.
Episode Video
Knee pain is one of the most common reasons people seek medical attention. It limits mobility, interferes with daily life, and is often assumed to be caused by a local joint issue. However, not all knee pain originates from the knee itself. In many cases, the real problem is rooted in the spine. This complex connection between knee pain and spine issues is the focus of a recent discussion between two seasoned specialists in spine surgery and interventional joint care.
Their conversation shines a light on the often-overlooked causes of leg and knee pain, exploring how compressed nerves in the spine can mimic joint problems, when surgical treatment is warranted, and how patient education and holistic preparation can lead to better outcomes.

Understanding the Knee Pain and Spine Issues Connection
It's easy to assume that pain near the knee is always due to a local injury or degeneration, such as arthritis or meniscus damage. However, the nerves that control sensation and movement in the legs originate in the lower back, and when those nerves become compressed or inflamed, they can send pain signals down into the thigh, calf, or knee. This is particularly true with conditions like L3 or L4 radiculopathy, where spinal nerve roots are affected and refer pain to specific regions of the leg.
Patients often question why a doctor examining knee pain would ask about their lower back or order spinal imaging. The reason lies in how interconnected the musculoskeletal and nervous systems are. A seemingly unrelated issue in the spine can manifest as localized knee discomfort or even weakness. Recognizing this knee pain and spine issues connection can prevent misdiagnoses and lead to more targeted, effective treatment.
Spotting Red Flags: When Spine Issues Become Surgical Emergencies
Certain spinal conditions require immediate surgical attention. One of the most critical red flags is progressive neurologic decline, such as foot drop or sudden weakness, caused by severe nerve compression. If left untreated, nerves under this type of pressure can suffer permanent damage.
Another urgent condition is cauda equina syndrome. While often misunderstood, early signs of this disorder include numbness in the legs, loss of sensation in the groin area, changes in bladder or bowel function, or even scrotal pain in males. These symptoms may be subtle at first, but they signal a serious issue in the lower spinal canal that demands rapid intervention to prevent long-term dysfunction.
Even after minimally invasive procedures like spinal injections, certain symptoms should not be ignored. Acute, worsening pain or weakness may indicate complications such as a spinal epidural hematoma, a collection of blood that compresses the spinal cord. These conditions illustrate the delicate balance of treating spine-related pain and the importance of proper timing and follow-up care.
Post-Surgical Pain That Persists: Looking Beyond the Operation
Spinal surgery isn’t always the end of the story. Some patients continue to experience knee pain or leg discomfort long after procedures such as discectomies or laminectomies. In these cases, doctors look for residual nerve compression, regrowth of bone spurs, or scarring that could be causing ongoing symptoms.
If imaging shows no obvious cause, physicians may turn to nerve conduction studies or EMGs to assess nerve function. Yet even these tests have limitations. Chronic symptoms that persist beyond one year post-surgery often indicate long-term nerve damage. Recovery in these situations depends heavily on the body’s ability to heal over time, supported by guided physical therapy and patient persistence.
Why Rehabilitation and Patient Optimization Matter
Surgery is not a shortcut to instant relief. Recovering from spinal interventions is a process that involves inflammation control, nerve regeneration, muscle retraining, and commitment to rehabilitation. To increase the chances of successful outcomes, doctors strongly encourage patients to prepare their bodies before undergoing any surgical or regenerative procedure.
This preparation includes stopping smoking, improving cardiovascular fitness, and ensuring optimal nutrition. Special attention is given to vitamin D and calcium levels, particularly in spinal fusion procedures, as deficiencies can contribute to nonunion and poor bone healing. Patients are advised to maintain a high-protein, low-fat diet and to include plenty of leafy greens and nutrient-dense foods. Walking regularly and building core strength are also key steps in surgical readiness.
Navigating the Healthcare System: The Reality of Delayed Care
Despite clear symptoms and supportive imaging, the healthcare system sometimes slows the path to treatment. Insurance companies often require a documented trial of conservative management, including physical therapy and anti-inflammatory medications, before approving surgical care. While diagnostic injections can aid in both pain relief and pinpointing the source of pain, physical therapy remains the most consistent prerequisite.
In some cases, delays in care due to these requirements can worsen outcomes, particularly when nerve damage progresses while awaiting clearance. Some practices have begun integrating in-house physical therapy services to streamline this process and ensure that patients don’t lose critical time between evaluation and treatment.
Rethinking the SI Joint: When Fusion Isn’t the Answer
Another debated topic in modern spine care is the minimally invasive sacroiliac (SI) joint fusion. The SI joint, which connects the spine to the pelvis, plays a key role in lower body motion. While fusions may be appropriate for patients who’ve already undergone lumbar spinal fusion, SI joint pain is often overdiagnosed in patients without prior hardware.
This procedure carries risks, especially when performed without strong diagnostic evidence. Improperly placed implants or lack of mechanical fixation can lead to poor outcomes and complicate future procedures such as hip replacements. Responsible doctors approach SI joint fusion with caution, requiring multiple diagnostic injections and pain diaries before considering surgery. In many cases, issues like hip dysfunction, gluteal tendonitis, or lower spine degeneration are the true source of the pain.
Treating Compression Fractures
Among the most impactful treatments discussed was the minimally invasive procedure used to treat vertebral compression fractures, a common condition in elderly patients with osteoporosis. These fractures can leave individuals bedridden and heavily dependent on opioids. However, a procedure known as balloon kyphoplasty can be performed in an outpatient setting and often yields immediate relief.
Using a specialized needle and a small balloon to restore height and space in the collapsed vertebra, the physician then injects cement to stabilize the bone. The result is often dramatic, patients who arrived in wheelchairs are frequently walking within minutes post-procedure. Beyond relieving pain, this approach restores independence and significantly improves quality of life. It also allows for follow-up care aimed at treating the underlying osteoporosis through medications, bone scans, and lifestyle adjustments.
A Holistic Approach to Long-Term Pain Management
Effective treatment for knee pain or spine issues doesn’t end with one surgery or procedure. The most successful outcomes happen when doctors focus on the whole person. That includes recognizing the overlapping causes of pain, thoroughly evaluating all potential sources, and empowering patients with tools and education to support their own recovery.
By taking a comprehensive approach, from diagnostic imaging and physical exams to nutrition, exercise, and mental wellness, doctors are helping patients not only reduce their pain but reclaim control over their lives.
About Dr. Harvinder Bedi

Meet Dr. Harvinder Bedi, a board-certified spine surgeon and leader in advanced spinal care. With specialized training from Cedars-Sinai and over a decade of experience treating complex cervical, thoracic, and lumbar spine disorders, he brings a powerful blend of innovation, precision, and patient-centered care to Phoenix and Sun City, Arizona. Whether treating degenerative conditions, spinal trauma, or performing minimally invasive procedures, Dr. Bedi is known for his expertise, compassion, and commitment to excellence.
To learn more, visit www.camelbackspine.com, or connect with Camelback Spine Care on Instagram and Facebook. Don’t miss your chance to work directly with a surgeon who puts patients first, and is redefining spine care from the ground up.
Final Thoughts
Knee pain and spine issues are often more connected than most people realize. Understanding this deeper relationship is crucial for finding lasting relief and avoiding unnecessary treatments. By taking a comprehensive approach that looks beyond the surface, patients have a real chance to heal, move better, and reclaim their quality of life. With the expertise shared in this episode, it’s clear that real recovery starts with the right diagnosis, and the right doctor by your side. Don’t ignore the signs your body is giving you; the right answers might be closer than you think.
If you're ready to take control of your knee pain, click here to discover more about these five effective knee pain home treatments. With these simple steps, you can start your journey towards pain-free knees and a more active lifestyle.